SigProfilerSuite/SigProfilerExtractorR

An R wrapper for SigProfilerExtractor that allows de novo extraction of mutational signatures from data generated in a matrix format. The tool identifies the number of operative mutational signatures, their activities in each sample, and the probability for each signature to cause a specific mutation type in a cancer sample. The tool makes use of SigProfilerMatrixGenerator and SigProfilerPlotting.

语言：R · GitHub 星标：15 · Fork：1

话题：bioinformatics · cancer-genomics · mutation-analysis · mutational-signatures · somatic-variants

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